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Peptide record

TPDB45804

Antiviral standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB45804
Antiviral
Anti-infective peptides
DRAVP 2.0
standard
No
A 21-aa standard natural antiviral peptide sequence curated from DRAVP 2.0, with an available 3D structural model.
Sequence
GSKKPVPIIYCNRRTGKCQRI
Physicochemical Analysis
C104H181N35O27S2
ADEHLMFW
RIK
2417.92
10.88
6
0
5
+6
5.31
-0.776
69.52
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1615
66.79
7
Residue Composition
number
0
A
3
R
1
N
0
D
2
C
0
E
1
Q
2
G
0
H
3
I
0
L
3
K
0
M
0
F
2
P
1
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 2 H: 0 I: 3 L: 0 K: 3 M: 0 F: 0 P: 2 S: 1 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
21
C104H181N35O27S2
2417.92
10.88
+6
5.31
-0.776
Evidence Records 1 records
Evidence 1 Activity

Activity

MIC
Antiviral
1.6 µM

Target

Escherichia coli ATCC 25922

Source & Reference

DRAVP 2.0

Other

IIB (EC50 13.1 ug/ml) HSV-2MS in Vero cells (EC50 2.32 g/ml). Also, active against Gram- E. coli ATCC 25922 (MIC 1.6 uM) (for ref, see AP5758). Warning: other bacteria not tested.