TPDB

3D PDB MODEL

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TPDB ID TPDB45397

Activity

Antiviral

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP 3.0

Sequence_Type

standard

Has_Modification No

Description A 241-aa standard natural antiviral peptide sequence curated from dbAMP 3.0, with an available 3D structural model.

Sequence

MGWSCIILFLVATATGSWAQSALTQPSSASASLGASVTLTCTLSSGYSNSAVDWHQQRPGKGPQFVMRVGTGGIVGSKGDGIPDRFSGSGSGLNRYLIIKNIQEEDESDYHCGADHGTGSAFVYVFGGGTKLTVLGQPKASPLVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS

FASTA

>TPDB45397|Antiviral|length=241
MGWSCIILFLVATATGSWAQSALTQPSSASASLGASVTLTCTLSSGYSNSAVDWHQQRPGKGPQFVMRVGTGGIVGSKGDGIPDRFSGSGSGLNRYLIIKNIQEEDESDYHCGADHGTGSAFVYVFGGGTKLTVLGQPKASPLVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPTECS

Formula C1112H1728N300O358S8

Absent Amino Acids

Common Amino Acids S

Mass 25284.23

PI 6.58

Basic Residues 22

Acidic Residues 18

Hydrophobic Residues 85

Net Charge -1

Boman Index 32.41

Hydrophobicity -0.186

Aliphatic Index 70.41

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 39795

Absorbance 280nm 157.39

Polar Residues 86

number

20

A

5

R

6

N

8

D

6

C

10

E

11

Q

25

G

5

H

8

I

17

L

12

K

2

M

7

F

13

P

34

S

21

T

5

W

8

Y

18

V

Amino Acid Distribution

A: 20 R: 5 N: 6 D: 8 C: 6 E: 10 Q: 11 G: 25 H: 5 I: 8 L: 17 K: 12 M: 2 F: 7 P: 13 S: 34 T: 21 W: 5 Y: 8 V: 18

Length

241

Formula

C1112H1728N300O358S8

Mass

25284.23

PI

6.58

Net Charge

-1

Boman Index

32.41

Hydrophobicity

-0.186

Evidence 1 Activity

Source & Reference

Database Source dbAMP 3.0

Other

Source Activity Label	Source Definition
Antiviral	dbAMP 3.0 classified under the Anti-viral function class.