TPDB

3D PDB MODEL

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TPDB ID TPDB45394

Activity

Antiviral

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP 3.0

Sequence_Type

standard

Has_Modification No

Description A 229-aa standard natural antiviral peptide sequence curated from dbAMP 3.0, with an available 3D structural model.

Sequence

QVQLQQSGPEVVKPGASVKMSCKASGYTFTSYVIHWVRQKPGQGLDWIGYINPYNDGTDYDEKFKGKATLTSDTSTSTAYMELSSLRSEDTAVYYCAREKDNYATGAWFAYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGDKTH

FASTA

>TPDB45394|Antiviral|length=229
QVQLQQSGPEVVKPGASVKMSCKASGYTFTSYVIHWVRQKPGQGLDWIGYINPYNDGTDYDEKFKGKATLTSDTSTSTAYMELSSLRSEDTAVYYCAREKDNYATGAWFAYWGQGTLVTVSSASTKGPSVFPLAPCSRSTSESTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTKTYTCNVDHKPSNTKVDKRVESKYGDKTH

Formula C1098H1683N287O352S7

Absent Amino Acids

Common Amino Acids S

Mass 24760.57

PI 8.08

Basic Residues 25

Acidic Residues 19

Hydrophobic Residues 80

Net Charge +2

Boman Index 32.98

Hydrophobicity -0.392

Aliphatic Index 62.10

Half Life

Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour

Extinction Coefficient Cystines 48610

Absorbance 280nm 196.32

Polar Residues 89

number

15

A

5

R

6

N

11

D

5

C

8

E

8

Q

18

G

4

H

3

I

14

L

16

K

2

M

6

F

12

P

32

S

24

T

5

W

14

Y

21

V

Amino Acid Distribution

A: 15 R: 5 N: 6 D: 11 C: 5 E: 8 Q: 8 G: 18 H: 4 I: 3 L: 14 K: 16 M: 2 F: 6 P: 12 S: 32 T: 24 W: 5 Y: 14 V: 21

Length

229

Formula

C1098H1683N287O352S7

Mass

24760.57

PI

8.08

Net Charge

+2

Boman Index

32.98

Hydrophobicity

-0.392

Evidence 1 Activity

Source & Reference

Database Source dbAMP 3.0

Other

Source Activity Label	Source Definition
Antiviral	dbAMP 3.0 classified under the Anti-viral function class.