TPDB

3D PDB MODEL

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TPDB ID TPDB45369

Activity

Antiviral

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP 3.0

Sequence_Type

standard

Has_Modification No

Description A 175-aa standard natural antiviral peptide sequence curated from dbAMP 3.0, with an available 3D structural model.

Sequence

MCRQELSGIVQKQNNLLRQIEAQQHLLQLTVSKIKQLQARILAVERYLKDQQLGKGNQPQQDKLYREVALIRAQLQKIESETLQLLHQQAEIERELNNQEQEIGSLKQRGCIDGPLLSGIDQQQNNLKRAIEAQKHLLQLTVWGIKQLQARILAVERYLKDQQLGGGGSHHHHHH

FASTA

>TPDB45369|Antiviral|length=175
MCRQELSGIVQKQNNLLRQIEAQQHLLQLTVSKIKQLQARILAVERYLKDQQLGKGNQPQQDKLYREVALIRAQLQKIESETLQLLHQQAEIERELNNQEQEIGSLKQRGCIDGPLLSGIDQQQNNLKRAIEAQKHLLQLTVWGIKQLQARILAVERYLKDQQLGGGGSHHHHHH

Formula C879H1459N277O262S3

Absent Amino Acids F

Common Amino Acids Q

Mass 20196.13

PI 9.70

Basic Residues 32

Acidic Residues 18

Hydrophobic Residues 62

Net Charge +6

Boman Index 58.61

Hydrophobicity -0.719

Aliphatic Index 107.03

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 10095

Absorbance 280nm 49.98

Polar Residues 52

number

10

A

11

R

7

N

5

D

2

C

13

E

31

Q

12

G

9

H

13

I

28

L

12

K

1

M

0

F

2

P

6

S

3

T

1

W

3

Y

6

V

Amino Acid Distribution

A: 10 R: 11 N: 7 D: 5 C: 2 E: 13 Q: 31 G: 12 H: 9 I: 13 L: 28 K: 12 M: 1 F: 0 P: 2 S: 6 T: 3 W: 1 Y: 3 V: 6

Length

175

Formula

C879H1459N277O262S3

Mass

20196.13

PI

9.70

Net Charge

+6

Boman Index

58.61

Hydrophobicity

-0.719

Evidence 1 Activity

Source & Reference

Database Source dbAMP 3.0

Other

Source Activity Label	Source Definition
Antiviral	dbAMP 3.0 classified under the Anti-viral function class.