TPDB

3D PDB MODEL

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TPDB ID TPDB45331

Activity

Antiviral

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP 3.0 DRAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 90-aa standard natural antiviral peptide sequence curated from dbAMP 3.0, DRAMP, and Peptipedia, with an available 3D structural model.

Sequence

MGKRLYAVAYDIPDDTRRVKLANLLKSYGERVQLSVFECYLDERLLEDLRRRARRLLDLGQDALRIYPVAGQVEVLGVGPLPELREVQVL

FASTA

>TPDB45331|Antiviral|length=90
MGKRLYAVAYDIPDDTRRVKLANLLKSYGERVQLSVFECYLDERLLEDLRRRARRLLDLGQDALRIYPVAGQVEVLGVGPLPELREVQVL

Formula C463H764N134O132S2

Absent Amino Acids HW

Common Amino Acids L

Mass 10384.10

PI 8.66

Basic Residues 15

Acidic Residues 14

Hydrophobic Residues 42

Net Charge +1

Boman Index 23.68

Hydrophobicity -0.180

Aliphatic Index 121.22

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 7450

Absorbance 280nm 71.74

Polar Residues 14

number

6

A

12

R

1

N

7

D

1

C

7

E

4

Q

6

G

0

H

2

I

17

L

3

K

1

M

1

F

4

P

2

S

1

T

0

W

5

Y

10

V

Amino Acid Distribution

A: 6 R: 12 N: 1 D: 7 C: 1 E: 7 Q: 4 G: 6 H: 0 I: 2 L: 17 K: 3 M: 1 F: 1 P: 4 S: 2 T: 1 W: 0 Y: 5 V: 10

Length

90

Formula

C463H764N134O132S2

Mass

10384.10

PI

8.66

Net Charge

+1

Boman Index

23.68

Hydrophobicity

-0.180

Evidence 1 Activity

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Source Activity Label	Source Definition
Antiviral	dbAMP 3.0 classified under the Anti-viral function class.