TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB45315

Activity

Antiviral

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP 3.0 DRAMP Peptipedia

Sequence_Type

modified_plain

Has_Modification Yes

Description A 60-aa modified antiviral peptide sequence curated from dbAMP 3.0, DRAMP, and Peptipedia, with an available 3D structural model.

Modification

Modified, details unspecified

Sequence

AVKTITLNLVSPSANRYATFLTEIRDNVRXRSLDYSHSGIDVIGAPSSRDSXLNINFQSP

FASTA

>TPDB45315|Antiviral|length=60
AVKTITLNLVSPSANRYATFLTEIRDNVRXRSLDYSHSGIDVIGAPSSRDSXLNINFQSP

Formula C278H448N82O90

Absent Amino Acids CMW

Common Amino Acids S

Mass 6379.11

PI 9.56

Basic Residues 7

Acidic Residues 5

Hydrophobic Residues 22

Net Charge +1

Boman Index 9.83

Hydrophobicity -0.253

Aliphatic Index 91.00

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 2980

Absorbance 280nm 46.71

Polar Residues 21

number

4

A

5

R

5

N

4

D

0

C

1

E

1

Q

2

G

1

H

5

I

5

L

1

K

0

M

2

F

3

P

9

S

4

T

0

W

2

Y

4

V

Amino Acid Distribution

A: 4 R: 5 N: 5 D: 4 C: 0 E: 1 Q: 1 G: 2 H: 1 I: 5 L: 5 K: 1 M: 0 F: 2 P: 3 S: 9 T: 4 W: 0 Y: 2 V: 4

Length

60

Formula

C278H448N82O90

Mass

6379.11

PI

9.56

Net Charge

+1

Boman Index

9.83

Hydrophobicity

-0.253

Evidence 1 Activity

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Source Activity Label	Source Definition
Antiviral	dbAMP 3.0 classified under the Anti-viral function class.