TPDB

3D PDB MODEL

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TPDB ID TPDB45274

Activity

Antiviral

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP 3.0

Sequence_Type

standard

Has_Modification No

Description A 262-aa standard natural antiviral peptide sequence curated from dbAMP 3.0, with an available 3D structural model.

Sequence

VNTIIYNVGSTTISKYATFLNDLRNEAKDPSLKCYGIPMLPNTNTNPKYVLVELQGSNKKTITLMLRRNNLYVMGYSDPFETNKCRYHIFNDISGTERQDVETTLCPNANSRVSKNINFDSRYPTLESKAGVKSRSQVQLGIQILDSNIGKISGVMSFTEKTEAEFLLVAIQMVSEAARFKYIENQVKTNFNRAFNPNPKVLNLQETWGKISTAIHDAKNGVLPKPLELVDASGAKWIVLRVDEIKPDVALLNYVGGSCQTT

FASTA

>TPDB45274|Antiviral|length=262
VNTIIYNVGSTTISKYATFLNDLRNEAKDPSLKCYGIPMLPNTNTNPKYVLVELQGSNKKTITLMLRRNNLYVMGYSDPFETNKCRYHIFNDISGTERQDVETTLCPNANSRVSKNINFDSRYPTLESKAGVKSRSQVQLGIQILDSNIGKISGVMSFTEKTEAEFLLVAIQMVSEAARFKYIENQVKTNFNRAFNPNPKVLNLQETWGKISTAIHDAKNGVLPKPLELVDASGAKWIVLRVDEIKPDVALLNYVGGSCQTT

Formula C1300H2081N355O396S9

Absent Amino Acids

Common Amino Acids N

Mass 29308.50

PI 9.21

Basic Residues 33

Acidic Residues 25

Hydrophobic Residues 101

Net Charge +6

Boman Index 54.15

Hydrophobicity -0.332

Aliphatic Index 88.51

Half Life

Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 26150

Absorbance 280nm 89.22

Polar Residues 87

number

14

A

11

R

25

N

11

D

4

C

14

E

9

Q

14

G

2

H

18

I

23

L

20

K

5

M

9

F

12

P

19

S

20

T

2

W

10

Y

20

V

Amino Acid Distribution

A: 14 R: 11 N: 25 D: 11 C: 4 E: 14 Q: 9 G: 14 H: 2 I: 18 L: 23 K: 20 M: 5 F: 9 P: 12 S: 19 T: 20 W: 2 Y: 10 V: 20

Length

262

Formula

C1300H2081N355O396S9

Mass

29308.50

PI

9.21

Net Charge

+6

Boman Index

54.15

Hydrophobicity

-0.332

Evidence 1 Activity

Source & Reference

Database Source dbAMP 3.0

Other

Source Activity Label	Source Definition
Antiviral	dbAMP 3.0 classified under the Anti-viral function class.