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Peptide record

TPDB45264

Antiviral standard
174 amino acids
Basic Information
3D PDB MODEL
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TPDB45264
Antiviral
Anti-infective peptides
dbAMP 3.0
standard
No
A 174-aa standard natural antiviral peptide sequence curated from dbAMP 3.0, with an available 3D structural model.
Sequence
MQSSILLIFAAFVACTYAQVSLPPGYAQKYPQYKYSKVARHPRDTTWEHNVGRGKIFGTLGSNDDSVFGRGGYKQDIFNDHRGRLSGQAYGSRVINDYGGSSILGGKLDWSNDNARAALDVHKEIGRGSGMKLSGDGVWKLDHNTRFSAGGNLQKNFGHNRPEFGIQGKIEHDF
Physicochemical Analysis
C851H1295N253O252S3
G
19198.37
9.78
29
16
61
+7
29.02
-0.646
64.48
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
28420
148.03
46
Residue Composition
number
11
A
11
R
10
N
12
D
1
C
4
E
8
Q
25
G
7
H
9
I
11
L
11
K
2
M
9
F
5
P
14
S
5
T
3
W
8
Y
8
V
Amino Acid Distribution
A: 11 R: 11 N: 10 D: 12 C: 1 E: 4 Q: 8 G: 25 H: 7 I: 9 L: 11 K: 11 M: 2 F: 9 P: 5 S: 14 T: 5 W: 3 Y: 8 V: 8
Chemical Descriptors
174
C851H1295N253O252S3
19198.37
9.78
+7
29.02
-0.646
Evidence Records 1 records
Evidence 1 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
TnGlv1 and TnGlv2 inactivate baculovirus BV in vitro. TnGlv2 has greater antiviral activity than TnGlv1. The peptide can rapidly lyse vesicles consisting of zwitterionic PC and anionic PG but not PC only, indicating the role of electrostatic interactions. Deposited2012April 25. Provided by Eric J Haas-Stapleton. . Updated 8/2025