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Peptide record

TPDB45263

Antiviral standard
163 amino acids
Basic Information
3D PDB MODEL
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TPDB45263
Antiviral
Anti-infective peptides
dbAMP 3.0
standard
No
A 163-aa standard natural antiviral peptide sequence curated from dbAMP 3.0, with an available 3D structural model.
Sequence
MQLSTIFCFAVLIACARAQVFVKPGHKDEDLAWMRSMGKGHVFGTLGSTDGSLIGKLGYKQNIYNDQRGNLGGTAYGSRVINEYGGTSSFGGKLDWKNANDNARASLDVHKQVGGSSGMTLTGDGVWKLDSKTRLVAGGNLDKTFGYSKPELGIQAKIEHDFK
Physicochemical Analysis
C773H1212N220O234S6
G
17523.82
9.57
24
15
60
+5
24.17
-0.366
73.01
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
24075
137.38
42
Residue Composition
number
11
A
6
R
8
N
11
D
2
C
4
E
6
Q
25
G
4
H
7
I
14
L
14
K
4
M
7
F
2
P
12
S
9
T
3
W
5
Y
9
V
Amino Acid Distribution
A: 11 R: 6 N: 8 D: 11 C: 2 E: 4 Q: 6 G: 25 H: 4 I: 7 L: 14 K: 14 M: 4 F: 7 P: 2 S: 12 T: 9 W: 3 Y: 5 V: 9
Chemical Descriptors
163
C773H1212N220O234S6
17523.82
9.57
+5
24.17
-0.366
Evidence Records 1 records
Evidence 1 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
TnGlv1 and TnGlv2 inactivate baculovirus BV in vitro. The peptide can rapidly lyse vesicles consisting of zwitterionic PC and anionic PG but not PC only, indicating the role of electrostatic interactions. Deposited2012April 25. Provided by Eric J Haas-Stapleton. Updated 8/2025.