TPDB

3D PDB MODEL

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TPDB ID TPDB45256

Activity

Antiviral

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP 3.0

Sequence_Type

standard

Has_Modification No

Description A 248-aa standard natural antiviral peptide sequence curated from dbAMP 3.0, with an available 3D structural model.

Sequence

MDVSFRLSGATSSSYGVFISNLRKALPNERKLYDIPLLRSSLPGSQRYALIHLTNYADETISVAIDVTNVYIMGYRAGDTSYFFNEASATEAAKYVFKDAMRKVTLPYSGNYERLQTAAGKIRENIPLGLPALDSAITTLFYYNANSAASALMVLIQSTSEAARYKFIEQQIGKRVDKTFLPSLAIISLENSWSALSKQIQIASTNNGQFESPVVLINAQNQRVTITNVDAGVVTSNIALLLNRNNMA

FASTA

>TPDB45256|Antiviral|length=248
MDVSFRLSGATSSSYGVFISNLRKALPNERKLYDIPLLRSSLPGSQRYALIHLTNYADETISVAIDVTNVYIMGYRAGDTSYFFNEASATEAAKYVFKDAMRKVTLPYSGNYERLQTAAGKIRENIPLGLPALDSAITTLFYYNANSAASALMVLIQSTSEAARYKFIEQQIGKRVDKTFLPSLAIISLENSWSALSKQIQIASTNNGQFESPVVLINAQNQRVTITNVDAGVVTSNIALLLNRNNMA

Formula C1217H1937N329O371S5

Absent Amino Acids C

Common Amino Acids A

Mass 27274.05

PI 9.49

Basic Residues 24

Acidic Residues 19

Hydrophobic Residues 115

Net Charge +4

Boman Index 26.78

Hydrophobicity -0.029

Aliphatic Index 98.02

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 24870

Absorbance 280nm 91.19

Polar Residues 84

number

28

A

13

R

19

N

9

D

0

C

10

E

10

Q

11

G

1

H

19

I

25

L

10

K

5

M

9

F

8

P

26

S

16

T

1

W

13

Y

15

V

Amino Acid Distribution

A: 28 R: 13 N: 19 D: 9 C: 0 E: 10 Q: 10 G: 11 H: 1 I: 19 L: 25 K: 10 M: 5 F: 9 P: 8 S: 26 T: 16 W: 1 Y: 13 V: 15

Length

248

Formula

C1217H1937N329O371S5

Mass

27274.05

PI

9.49

Net Charge

+4

Boman Index

26.78

Hydrophobicity

-0.029

Evidence 1 Activity

Source & Reference

Database Source dbAMP 3.0

Other

Source Activity Label	Source Definition
Antiviral	dbAMP 3.0 classified under the Anti-viral function class.