TPDB

3D PDB MODEL

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TPDB ID TPDB45234

Activity

Antiviral

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP 3.0

Sequence_Type

standard

Has_Modification No

Description A 261-aa standard natural antiviral peptide sequence curated from dbAMP 3.0, with an available 3D structural model.

Sequence

INTITFDAGNATINKYATFMESLRNEAKDPSLKCYGIPMLPNTNSTIKYLLVKLQGASLKTITLMLRRNNLYVMGYSDPYDNKCRYHIFNDIKGTEYSDVENTLCPSSNPRVAKPINYNGLYPTLEKKAGVTSRNEVQLGIQILSSDIGKISGQGSFTEKIEAKFLLVAIQMVSEAARFKYIENQVKTNFNRDFSPNDKVLDLEENWGKISTAIHNSKNGALPKPLELKNADGTKWIVLRVDEIKPDVGLLNYVNGTCQAT

FASTA

>TPDB45234|Antiviral|length=261
INTITFDAGNATINKYATFMESLRNEAKDPSLKCYGIPMLPNTNSTIKYLLVKLQGASLKTITLMLRRNNLYVMGYSDPYDNKCRYHIFNDIKGTEYSDVENTLCPSSNPRVAKPINYNGLYPTLEKKAGVTSRNEVQLGIQILSSDIGKISGQGSFTEKIEAKFLLVAIQMVSEAARFKYIENQVKTNFNRDFSPNDKVLDLEENWGKISTAIHNSKNGALPKPLELKNADGTKWIVLRVDEIKPDVGLLNYVNGTCQAT

Formula C1300H2073N349O395S9

Absent Amino Acids

Common Amino Acids NL

Mass 29200.40

PI 8.98

Basic Residues 34

Acidic Residues 27

Hydrophobic Residues 101

Net Charge +5

Boman Index 53.20

Hydrophobicity -0.382

Aliphatic Index 88.54

Half Life

Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 29130

Absorbance 280nm 99.76

Polar Residues 83

number

15

A

9

R

25

N

13

D

4

C

14

E

7

Q

16

G

2

H

20

I

25

L

23

K

5

M

8

F

12

P

17

S

18

T

2

W

12

Y

14

V

Amino Acid Distribution

A: 15 R: 9 N: 25 D: 13 C: 4 E: 14 Q: 7 G: 16 H: 2 I: 20 L: 25 K: 23 M: 5 F: 8 P: 12 S: 17 T: 18 W: 2 Y: 12 V: 14

Length

261

Formula

C1300H2073N349O395S9

Mass

29200.40

PI

8.98

Net Charge

+5

Boman Index

53.20

Hydrophobicity

-0.382

Evidence 1 Activity

Source & Reference

Database Source dbAMP 3.0

Other

Source Activity Label	Source Definition
Antiviral	dbAMP 3.0 classified under the Anti-viral function class.