TPDB

3D PDB MODEL

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TPDB ID TPDB45225

Activity

Antiviral

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP 3.0

Sequence_Type

standard

Has_Modification No

Description A 202-aa standard natural antiviral peptide sequence curated from dbAMP 3.0, with an available 3D structural model.

Sequence

GPLGSPGFEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVKLNQRRGFLANQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIKTARIYDDQGRAQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGAPFQPWDGLDEHSQDLSGRLRAILQNQEN

FASTA

>TPDB45225|Antiviral|length=202
GPLGSPGFEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVKLNQRRGFLANQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIKTARIYDDQGRAQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGAPFQPWDGLDEHSQDLSGRLRAILQNQEN

Formula C1048H1568N296O301S11

Absent Amino Acids

Common Amino Acids L

Mass 23482.44

PI 6.20

Basic Residues 32

Acidic Residues 26

Hydrophobic Residues 73

Net Charge -3

Boman Index 41.14

Hydrophobicity -0.592

Aliphatic Index 64.26

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 40825

Absorbance 280nm 173.85

Polar Residues 53

number

12

A

13

R

9

N

13

D

7

C

13

E

11

Q

13

G

10

H

8

I

17

L

9

K

4

M

14

F

10

P

11

S

10

T

6

W

5

Y

7

V

Amino Acid Distribution

A: 12 R: 13 N: 9 D: 13 C: 7 E: 13 Q: 11 G: 13 H: 10 I: 8 L: 17 K: 9 M: 4 F: 14 P: 10 S: 11 T: 10 W: 6 Y: 5 V: 7

Length

202

Formula

C1048H1568N296O301S11

Mass

23482.44

PI

6.20

Net Charge

-3

Boman Index

41.14

Hydrophobicity

-0.592

Evidence 1 Activity

Source & Reference

Database Source dbAMP 3.0

Other

Source Activity Label	Source Definition
Antiviral	dbAMP 3.0 classified under the Anti-viral function class.