TPDB

3D PDB MODEL

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TPDB ID TPDB45214

Activity

Antiviral

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP 3.0

Sequence_Type

standard

Has_Modification No

Description A 247-aa standard natural antiviral peptide sequence curated from dbAMP 3.0, with an available 3D structural model.

Sequence

DVSFRLSGATSSSYGVFISNLRKALPNERKLYDIPLLRSSLPGSQRYALIHLTNYADETISVAIDVTNVYIMGYRAGDTSYFFNEASATEAAKYVFKDAMRKVTLPYSGNYERLQTAAGKIRENIPLGLPALDSAITTLFYYNANSAASALMVLIQSTSEAARYKFIEQQIGKRVDKTFLPSLAIISLENSWSALSKQIQIASTNNGQFESPVVLINAQNQRVTITNVDAGKVTSDIALLLNRNNMA

FASTA

>TPDB45214|Antiviral|length=247
DVSFRLSGATSSSYGVFISNLRKALPNERKLYDIPLLRSSLPGSQRYALIHLTNYADETISVAIDVTNVYIMGYRAGDTSYFFNEASATEAAKYVFKDAMRKVTLPYSGNYERLQTAAGKIRENIPLGLPALDSAITTLFYYNANSAASALMVLIQSTSEAARYKFIEQQIGKRVDKTFLPSLAIISLENSWSALSKQIQIASTNNGQFESPVVLINAQNQRVTITNVDAGKVTSDIALLLNRNNMA

Formula C1213H1930N328O371S4

Absent Amino Acids C

Common Amino Acids A

Mass 27172.88

PI 9.48

Basic Residues 25

Acidic Residues 20

Hydrophobic Residues 113

Net Charge +4

Boman Index 28.74

Hydrophobicity -0.069

Aliphatic Index 97.25

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour

Extinction Coefficient Cystines 24870

Absorbance 280nm 91.53

Polar Residues 83

number

28

A

13

R

18

N

10

D

0

C

10

E

10

Q

11

G

1

H

19

I

25

L

11

K

4

M

9

F

8

P

26

S

16

T

1

W

13

Y

14

V

Amino Acid Distribution

A: 28 R: 13 N: 18 D: 10 C: 0 E: 10 Q: 10 G: 11 H: 1 I: 19 L: 25 K: 11 M: 4 F: 9 P: 8 S: 26 T: 16 W: 1 Y: 13 V: 14

Length

247

Formula

C1213H1930N328O371S4

Mass

27172.88

PI

9.48

Net Charge

+4

Boman Index

28.74

Hydrophobicity

-0.069

Evidence 1 Activity

Source & Reference

Database Source dbAMP 3.0

Other

Source Activity Label	Source Definition
Antiviral	dbAMP 3.0 classified under the Anti-viral function class.