Back to search

Peptide record

TPDB44888

Antifungal Antiviral standard
29 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB44888
Antifungal Antiviral
Anti-infective peptides
Antifungipept AI4AVP dbAMP 3.0 DRAMP Peptipedia
standard
No
A 29-aa standard natural multi-activity (Antifungal and Antiviral) peptide sequence curated from Antifungipept, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
KVCYRAIPCGESCVWIPCISAAIGCSCKN
Physicochemical Analysis
C131H212N36O37S6
DQHLMFT
C
3075.70
8.02
3
1
11
+2
0.70
0.652
84.14
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
7365
239.46
11
Residue Composition
number
3
A
1
R
1
N
0
D
6
C
1
E
0
Q
2
G
0
H
4
I
0
L
2
K
0
M
0
F
2
P
3
S
0
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 3 R: 1 N: 1 D: 0 C: 6 E: 1 Q: 0 G: 2 H: 0 I: 4 L: 0 K: 2 M: 0 F: 0 P: 2 S: 3 T: 0 W: 1 Y: 1 V: 2
Chemical Descriptors
29
C131H212N36O37S6
3075.70
8.02
+2
0.70
0.652
Evidence Records 2 records
Evidence 1 Activity

Activity

Antifungal

Source & Reference

DRAMP Antifungipept

Other

Circulins C-F showed anti HIV-1 effect with EC50 values (concentration for 50% inhibition) in the range from 50 to 275 nM, depending upon the particular virus strain and host cell line used in the assay. Updated 7/2021
Evidence 2 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
Circulins C-F showed anti HIV-1 effect with EC50 values (concentration for 50% inhibition) in the range from 50 to 275 nM, depending upon the particular virus strain and host cell line used in the assay. Updated 7/2021