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Peptide record

TPDB44186

TAT-C-GNP Antiviral Cell-penetrating Peptides standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB44186
TAT-C-GNP
Antiviral Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
AI4AVP DRAVP 2.0 Peptipedia CellPPD CPPsite3.0 PerseuCPP
standard
No
A 11-aa standard natural multi-activity (Antiviral and Cell-penetrating Peptides) peptide sequence curated from AI4AVP, DRAVP 2.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Addition of Cysteine
Sequence
GRKKRRQRRRC
Physicochemical Analysis
C58H114N32O13S1
ANDEHILMFPSTWYV
R
1499.81
12.71
8
0
0
+8
7.19
-3.291
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
6
R
0
N
0
D
1
C
0
E
1
Q
1
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C58H114N32O13S1
1499.81
12.71
+8
7.19
-3.291
Addition of Cysteine
L
Cationic
Linear
Free
NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, MDA-MB-231 And A432 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Gold Nanoparticles
TAT-C-GNP, 16.9% and 17.6% were internalized by MDA-MB- 231 and A431 respectively after 2h incubation
In vitro
CCCCSSSSCCC
Additional Detail Fields 1 fields
CCCCSSSSCCC