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Peptide record

TPDB43338

Antifungal Antiviral standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB43338
Antifungal Antiviral
Anti-infective peptides
Antifungipept AI4AVP dbAMP 3.0 DRAMP Peptipedia
standard
No
A 31-aa standard natural multi-activity (Antifungal and Antiviral) peptide sequence curated from Antifungipept, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
KIPCGESCVWIPCVTSIFNCKCKENKVCYHD
Physicochemical Analysis
C154H240N40O44S6
ARQLM
C
3548.20
7.63
5
3
9
+1
6.26
-0.016
65.81
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
7365
207.57
12
Residue Composition
number
0
A
0
R
2
N
1
D
6
C
2
E
0
Q
1
G
1
H
3
I
0
L
4
K
0
M
1
F
2
P
2
S
1
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 2 D: 1 C: 6 E: 2 Q: 0 G: 1 H: 1 I: 3 L: 0 K: 4 M: 0 F: 1 P: 2 S: 2 T: 1 W: 1 Y: 1 V: 3
Chemical Descriptors
31
C154H240N40O44S6
3548.20
7.63
+1
6.26
-0.016
Evidence Records 2 records
Evidence 1 Activity

Activity

Antifungal

Source & Reference

DRAMP Antifungipept

Other

Circulins C-F showed anti HIV-1 effect with EC50 values (concentration for 50% inhibition) in the range from 50 to 275 nM, depending upon the particular virus strain and host cell line used in the assay. Updated 7/2021
Evidence 2 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
Circulins C-F showed anti HIV-1 effect with EC50 values (concentration for 50% inhibition) in the range from 50 to 275 nM, depending upon the particular virus strain and host cell line used in the assay. Updated 7/2021