Peptide record

TPDB43329

AAP-H Anticancer standard
5 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB43329
AAP-H
Anticancer
Cancer-related peptides
CancerPPD 2.0 dbACP
standard
No
A 5-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0 and dbACP, with an available 3D structural model.
Sequence
YVPGP
Physicochemical Analysis
C26H37N5O7
ARNDCEQHILKMFSTW
P
531.61
5.94
0
0
2
-0
0.04
-0.140
58.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
280.28
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
5
C26H37N5O7
531.61
5.94
-0
0.04
-0.140
Free
L
Linear
Free
Anticancer
Anthopleura anjunae
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 2.298 mM
Anticancer
2.298 mM

Target

Prostate Cancer
DU-145
Prostate

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0 dbACP
CancerPPD2
2018

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.