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Peptide record

TPDB43320

Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB43320
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
YSAYPDSVPMMS
Physicochemical Analysis
C59H86N12O20S2
RNCEQGHILKFTW
S
1347.52
3.10
0
1
6
-1
0.08
-0.158
32.50
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
2980
221.15
5
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
2
M
0
F
2
P
3
S
0
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 2 F: 0 P: 2 S: 3 T: 0 W: 0 Y: 2 V: 1
Chemical Descriptors
12
C59H86N12O20S2
1347.52
3.10
-1
0.08
-0.158
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor vessel
Targeting
Pancreatic islet tumors
Epinephrine-A

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeting pancreatic islets with phage display assisted by laser pressure catapult microdissection
2005
Yao VJ et al. Am J Pathol. 2005 Feb 166(2):625-36.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
EphA2-Fc protein and to the EphA2 receptor expressed on human umbilical vein endothelial cells , MDA-MB-435 cultured human breast carcinoma cells
Male C57BL/6/RIP-Tag2 transgenic mice
Phage display library
Phage/ CX7C peptide library
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Oncolytic T7 bacteriophage having cytokine gene and displaying homing peptide on capsid and its use for treating melanoma
2022
US 11384338 B2
US 11384338 B2

Other

6-week-old female Balb/C mice
Phage display library
T7 phage
Additional Detail Fields 3 fields
EphA2-Fc protein and to the EphA2 receptor expressed on human umbilical vein endothelial cells , MDA-MB-435 cultured human breast carcinoma cells
Male C57BL/6/RIP-Tag2 transgenic mice 6-week-old female Balb/C mice
Phage/ CX7C peptide library T7 phage