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Peptide record

TPDB43294

Sur-X Anticancer standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB43294
Sur-X
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 35-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
N-terminal: TAT Peptide
Sequence
YGRKKRRQRRRKDHRISTFKNWPFLEGCACTPERM
Physicochemical Analysis
C190H308N68O48S3
V
R
4409.14
11.68
13
3
8
+9
12.20
-1.660
25.14
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
7115
161.37
8
Residue Composition
number
1
A
8
R
1
N
1
D
2
C
2
E
1
Q
2
G
1
H
1
I
1
L
4
K
1
M
2
F
2
P
1
S
2
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 8 N: 1 D: 1 C: 2 E: 2 Q: 1 G: 2 H: 1 I: 1 L: 1 K: 4 M: 1 F: 2 P: 2 S: 1 T: 2 W: 1 Y: 1 V: 0
Chemical Descriptors
35
C190H308N68O48S3
4409.14
11.68
+9
12.20
-1.660
Free
L
Linear
TAT Peptide
Anticancer
Synthetic
Evidence Records 4 records
Evidence 1 Activity

Activity

20% cell viability at at 20 µM
Anticancer

Target

Colon Cancer
HCT-116
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

Not Available
Anticancer

Target

Colon Cancer
HCT-15
Colon

Assay & Model

MTT assay
Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2021
Evidence 3 Activity

Activity

25% cell viability at at 20 µM
Anticancer

Target

Colon Cancer
RKO
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021
Evidence 4 Activity

Activity

Not Available
Anticancer

Target

Colon Cancer
HT-29
Colon

Assay & Model

MTT assay
Not Available

Source & Reference

CancerPPD 2.0
CancerPPD2
2021