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Peptide record

TPDB43289

LJP-11 Anticancer standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB43289
LJP-11
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 6-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
YEHSHG
Physicochemical Analysis
C31H40N10O11
ARNDCQILKMFPTWV
H
728.72
6.01
2
1
1
-1
3.14
-2.067
0.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
204.47
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
1
G
2
H
0
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 2 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
6
C31H40N10O11
728.72
6.01
-1
3.14
-2.067
Free
L
Linear
Free
Anticancer
Laminaria japonica
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 0.49 ± 0.05 mM
Anticancer
0.49

Target

Liver Cancer
Huh-7
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 0.61 ± 0.07 mM
Anticancer
0.61

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022
Evidence 3 Activity

Activity

IC50
IC50 = 0.70 ± 0.07 mM
Anticancer
0.70

Target

Liver Cancer
H-22
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022