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Peptide record

TPDB43266

[TOAC1, Lys5,6] TG Anticancer modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB43266
[TOAC1, Lys5,6] TG
Anticancer
Cancer-related peptides
CancerPPD 2.0
modified_plain
Yes
A 10-aa modified anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Lol = leucinol Chemical: X = 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid, U = 2-Aminoisobutyric acid N-terminal: Oct = 1-octanoyl
Sequence
XGLUKKLUGI
Physicochemical Analysis
C34H65N9O8
ARNDCEQHMFPSTWYV
GLK
727.95
10.60
2
0
3
+2
0.57
0.350
117.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
2
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 2 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C34H65N9O8
727.95
10.60
+2
0.57
0.350
Lol = leucinol
X = 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid, U = 2-Aminoisobutyric acid
L
Linear
Oct = 1-octanoyl
AMP, Anticancer
Trichogin GA
Evidence Records 2 records
Evidence 1 Activity

Activity

EC50
EC50 = 10 µM
Anticancer
10 µM

Target

Brain Tumor
T-67
Brain

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2016

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

EC50
EC50 = 6 µM
Anticancer
6 µM

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2016