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Peptide record

TPDB43263

[TOAC1] TG Anticancer modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB43263
[TOAC1] TG
Anticancer
Cancer-related peptides
CancerPPD 2.0
modified_plain
Yes
A 10-aa modified anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Lol = leucinol Chemical: X = 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid, U = 2-Aminoisobutyric acid N-terminal: Oct = 1-octanoyl
Sequence
XGLUGGLUGI
Physicochemical Analysis
C26H47N7O8
ARNDCEQHKMFPSTWYV
G
585.70
6.02
0
0
3
-0
-1.39
1.050
117.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
1
I
2
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 2 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C26H47N7O8
585.70
6.02
-0
-1.39
1.050
Lol = leucinol
X = 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid, U = 2-Aminoisobutyric acid
L
Linear
Oct = 1-octanoyl
AMP, Anticancer
Trichogin GA
Evidence Records 2 records
Evidence 1 Activity

Activity

EC50
EC50 = 1 µM
Anticancer
1 µM

Target

Brain Tumor
T-67
Brain

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2016

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

EC50
EC50 = 3 µM
Anticancer
3 µM

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2016