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Peptide record

TPDB43245

Clone 40 Anticancer Tumor-homing Peptides modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB43245
Clone 40
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia TumorHoPe2.0
modified_plain
Yes
A 10-aa modified multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia and TumorHoPe2.0, with an available 3D structural model.
C-terminal: C-terminal hydrophobic Phe or Leu was replaced with a basic Lys residue N-terminal: N-terminal was conjugated with?â???é??-alanine (spacer) followed byFITC coupling
Sequence
WXEPAYQRKL
Physicochemical Analysis
C56H83N15O14
NDCGHIMFSTV
AREQLKPWY
1190.37
9.74
2
1
4
+1
1.33
-1.360
49.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
6990
587.21
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
1
E
1
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
1
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
10
C56H83N15O14
1190.37
9.74
+1
1.33
-1.360
C-terminal hydrophobic Phe or Leu was replaced with a basic Lys residue
N-terminal was conjugated with?â???é??-alanine (spacer) followed byFITC coupling
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptide arrays for screening cancer specific peptides
2010
Ahmed S et al. Anal Chem. 2010 Sep 15 82(18):7533-41.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human cancer cell line MDA-MB-435 & MCF-7
Synthetic
FITC
Additional Detail Fields 2 fields
FITC
Human cancer cell line MDA-MB-435 & MCF-7