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Peptide record

TPDB43212

Anticancer standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB43212
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 7-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
WQWRWQW-NH2
Physicochemical Analysis
C60H70N16O10
ANDCEGHILKMFPSTYV
W
1175.32
11.05
1
0
4
+1
-5.43
-2.157
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
22000
1871.84
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
2
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
7
C60H70N16O10
1175.32
11.05
+1
-5.43
-2.157
Amidation
L
Linear
Free
Antibacterial and Anticancer
Synthetic analogue of LfcinB(21-25)Pal
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 105 µM
Anticancer
105 µM

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 > 170 µM
Anticancer
170 µM

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023