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Peptide record

TPDB43192

Sample Peptide 3 from US011339203B2 Anticancer standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB43192
Sample Peptide 3 from US011339203B2
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 35-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
WFLREGSMFVALSASVFSLLAIKKRTLRKNDRKKR-NH2
Physicochemical Analysis
C189H315N57O46S1
CQHPY
RLK
4153.99
12.26
10
2
16
+8
4.39
-0.289
92.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
132.40
6
Residue Composition
number
3
A
5
R
1
N
1
D
0
C
1
E
0
Q
1
G
0
H
1
I
5
L
5
K
1
M
3
F
0
P
4
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 5 N: 1 D: 1 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 1 L: 5 K: 5 M: 1 F: 3 P: 0 S: 4 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
35
C189H315N57O46S1
4153.99
12.26
+8
4.39
-0.289
Amidation
L
Linear
Free
Anticancer
Synthetic
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell Viability
Cell Viability = 45.8% at 25 µM
Anticancer

Target

Renal Cancer
CAKI-2
Kidney

Assay & Model

CCK-8 assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022
US011339203B2

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.