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Peptide record

TPDB43181

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) Anticancer iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB43181
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
Anticancer iDPPIV
Cardiometabolic peptides Cancer-related peptides
CancerPPD 2.0 iDPPIV Peptipedia
standard
No
A 2-aa standard natural multi-activity (Anticancer and iDPPIV) peptide sequence curated from CancerPPD 2.0, iDPPIV, and Peptipedia, with an available 3D structural model.
Sequence
WD
Physicochemical Analysis
C15H17N3O5
ARNCEQGHILKMFPSTYV
DW
319.32
3.10
0
1
1
-1
-0.62
-2.200
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
1722.43
0
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
2
C15H17N3O5
319.32
3.10
-1
-0.62
-2.200
319.3119
319.1164
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73, 2015
2015
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@]([H])(CC(=O)O)C(=O)O InChI=1S/C15H17N3O5/c16-10(14(21)18-12(15(22)23)6-13(19)20)5-8-7-17-11-4-2-1-3-9(8)11/h1-4,7,10,12,17H,5-6,16H2,(H,18,21)(H,19,20)(H,22,23)/t10-,12-/m0/s1 InChIKey=PEEAINPHPNDNGE-JQWIXIFHSA-N PPARγ antagonist according to the BIOPEP-UWM database of bioactive peptides the ChEMBL database
Additional Detail Fields 1 fields
2