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Peptide record

TPDB43178

LCP-2 Anticancer standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB43178
LCP-2
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 4-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Cyclized N-terminal: Cyclized
Sequence
WAHT
Physicochemical Analysis
C24H31N7O6
RNDCEQGILKMFPSYV
AHTW
513.55
7.85
1
0
2
+0
-0.92
-0.750
25.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
1070.97
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
4
C24H31N7O6
513.55
7.85
+0
-0.92
-0.750
Cyclized
L
Cyclic
Cyclized
Anticancer
Laminaria japonica
Evidence Records 4 records
Evidence 1 Activity

Activity

IC50
IC50 = 116 ± 12.4 µM
Anticancer
116

Target

Gastric Cancer
SGC-7901
Stomach

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 107 ± 11.8 µM
Anticancer
107

Target

Gastric Cancer
MKN-45
Stomach

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021
Evidence 3 Activity

Activity

IC50
IC50 = 96.9 ± 9.91 µM
Anticancer
96.9

Target

Gastric Cancer
HepG-2
Stomach

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021
Evidence 4 Activity

Activity

IC50
IC50 = 100 ± 11.6 µM
Anticancer
100

Target

Colon Cancer
CaCo-2
Colon

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021