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Peptide record

TPDB43176

Anticancer Tumor-homing Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB43176
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 20-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
VYAQCGVNVRTGRGGCSRLM
Physicochemical Analysis
C86H147N31O26S3
DEHIKFPW
G
2127.49
9.92
3
0
7
+3
1.57
0.010
68.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1615
75.91
7
Residue Composition
number
1
A
3
R
1
N
0
D
2
C
0
E
1
Q
4
G
0
H
0
I
1
L
0
K
1
M
0
F
0
P
1
S
1
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 1 R: 3 N: 1 D: 0 C: 2 E: 0 Q: 1 G: 4 H: 0 I: 0 L: 1 K: 0 M: 1 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 1 V: 3
Chemical Descriptors
20
C86H147N31O26S3
2127.49
9.92
+3
1.57
0.010
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing (Phage display clone)
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of tumor-binding ligands in cancer patients with phage display libraries
2006
Krag DN et al. Cancer Res. 2006 Aug 1 66(15):7724-33.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
Phage display library
M13 phage/Random 20 mer (X4CX10CX4) peptide library
Additional Detail Fields 2 fields
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
M13 phage/Random 20 mer (X4CX10CX4) peptide library