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Peptide record

TPDB43157

p160 T160 Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB43157
p160 T160
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia dbACP StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, dbACP, StackTHP, and other sources, with an available 3D structural model.
Sequence
VPWMEPAYQRFL
Physicochemical Analysis
C74H105N17O17S1
NDCGHIKST
P
1536.81
6.90
1
1
7
-0
-0.50
-0.200
65.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
6990
454.84
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
1
E
1
Q
0
G
0
H
0
I
1
L
0
K
1
M
1
F
2
P
0
S
0
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 0 M: 1 F: 1 P: 2 S: 0 T: 0 W: 1 Y: 1 V: 1
Chemical Descriptors
12
C74H105N17O17S1
1536.81
6.90
-0
-0.50
-0.200
PW
Evidence Records 4 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Human neuroblastoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Neuroblastoma tumor cell-binding peptides identified through random peptide phage display
2001
Zhang J et al. Cancer Lett. 2001 Oct 10 171(2):153-64.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Neuroblastoma cell lines WAC
Phage display library
M13 phage /12 mer peptide library
Iodinated
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Neuroblastoma and breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Neuroblastoma tumor cell-binding peptides identified through random peptide phage display
2001
Zhang J et al. Cancer Lett. 2001 Oct 10 171(2):153-64.

Other

Human neuroblastoma cell lines WAC-2, Human breast cancer cell line MDA-MB-435
Phage display library
M13 phage /12 mer peptide library
FITC
Evidence 3 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Neuroblastoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Compositions of a peptide targeting system for treating cancer
2014
US 8680045 B2
US 8680045 B2

Other

SK-N-BE(1), SK-N-BE(2)
Nude mice (20 g)
Phage display library
Cy5.5
Evidence 4 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Protease inhibitor:protease sensitive expression system, composition and methods for improving the therapeutic activity and specificity of proteins delivered by bacteria
2022
US 11219671 B1
US 11219671 B1

Other

MDA-MB435 breast cancer
Salmonella typhimurium
Phage display library
Ph.D-7 Phage Display
Additional Detail Fields 4 fields
Iodinated FITC Cy5.5
Neuroblastoma cell lines WAC Human neuroblastoma cell lines WAC-2, Human breast cancer cell line MDA-MB-435 SK-N-BE(1), SK-N-BE(2) MDA-MB435 breast cancer
Nude mice (20 g) Salmonella typhimurium
M13 phage /12 mer peptide library Ph.D-7 Phage Display