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Peptide record

TPDB43129

Anticancer Tumor-homing Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB43129
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 20-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
VHMNCSWMRVSEGHPCESAD
Physicochemical Analysis
C92H139N29O31S4
QILKFTY
S
2275.53
5.17
3
3
6
-2
6.45
-0.560
34.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
5625
247.19
6
Residue Composition
number
1
A
1
R
1
N
1
D
2
C
2
E
0
Q
1
G
2
H
0
I
0
L
0
K
2
M
0
F
1
P
3
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 1 C: 2 E: 2 Q: 0 G: 1 H: 2 I: 0 L: 0 K: 0 M: 2 F: 0 P: 1 S: 3 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
20
C92H139N29O31S4
2275.53
5.17
-2
6.45
-0.560
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing (Phage display clone)
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of tumor-binding ligands in cancer patients with phage display libraries
2006
Krag DN et al. Cancer Res. 2006 Aug 1 66(15):7724-33.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
Phage display library
M13 phage/Random 20 mer (X4CX10CX4) peptide library
Additional Detail Fields 2 fields
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
M13 phage/Random 20 mer (X4CX10CX4) peptide library