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Peptide record

TPDB43108

FLAK50 Q1V Anticancer standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB43108
FLAK50 Q1V
Anticancer
Cancer-related peptides
AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb iACP-DRLF
standard
No
A 13-aa standard natural anticancer peptide sequence curated from AntiCP 2.0, CancerPPD 2.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
VAKFLAKFLKKAL-NH2
Physicochemical Analysis
C74H125N17O14
RNDCEQGHIMPSTWY
K
1476.91
11.00
4
0
9
+4
-0.42
0.846
135.38
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
3
L
4
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 4 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C74H125N17O14
1476.91
11.00
+4
-0.42
0.846
Amidation
L
Linear
Free
Anticancer
FLAK peptides
Evidence Records 3 records
Evidence 1 Activity

Activity

LD50
LD50 =92 µg/ml
Anticancer
92 µg/mL

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 SATPdb
CancerPPD2
2005
US_06875744_B2

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

Not Available
Anticancer

Target

Colon Cancer
SW-480
Colon

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 SATPdb
CancerPPD2
2005
US_06875744_B2
Evidence 3 Activity

Activity

Not Available
Anticancer

Target

Skin Cancer
BMKC
Skin

Assay & Model

MTT/MTS assay
24-h

Source & Reference

CancerPPD 2.0 SATPdb
CancerPPD2
2005
US_06875744_B2