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Peptide record

TPDB43104

[Arg2] TG Anticancer modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB43104
[Arg2] TG
Anticancer
Cancer-related peptides
CancerPPD 2.0
modified_plain
Yes
A 10-aa modified anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Lol = leucinol Chemical: U = 2-Aminoisobutyric acid N-terminal: Oct = 1-octanoyl
Sequence
URLUGGLUGI
Physicochemical Analysis
C30H56N10O8
ANDCEQHKMFPSTWYV
G
684.84
11.05
1
0
3
+1
-0.59
0.640
117.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
2
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 2 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C30H56N10O8
684.84
11.05
+1
-0.59
0.640
Lol = leucinol
U = 2-Aminoisobutyric acid
L
Linear
Oct = 1-octanoyl
AMP, Anticancer
Trichogin GA
Evidence Records 2 records
Evidence 1 Activity

Activity

EC50
EC50 = 8 µM
Anticancer
8 µM

Target

Brain Tumor
T-67
Brain

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2016

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

EC50
EC50 = 4 µM
Anticancer
4 µM

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2016