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Peptide record

TPDB43097

Api8-NH2 Anticancer modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB43097
Api8-NH2
Anticancer
Cancer-related peptides
CancerPPD 2.0
modified_plain
Yes
A 10-aa modified anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
C-terminal: Amidation Chemical: Z =4-aminopiperidine-4-carboxylic acid , U = 2-Aminoisobutyric acid N-terminal: Oct = 1-octanoyl
Sequence
UGLUGGLZGI-NH2
Physicochemical Analysis
C26H47N7O8
ARNDCEQHKMFPSTWYV
G
585.70
6.02
0
0
3
-0
-1.39
1.050
117.00
Mammalian: Yeast: E.coli:
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
1
I
2
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 1 L: 2 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C26H47N7O8
585.70
6.02
-0
-1.39
1.050
Amidation
Z =4-aminopiperidine-4-carboxylic acid , U = 2-Aminoisobutyric acid
L
Linear
Oct = 1-octanoyl
Antimicrobial and Antifungal
Trichogin GA
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 > 20 µM
Anticancer
20 µM

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTS assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.