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Peptide record

TPDB43080

BF2d Anticancer Cell-penetrating Peptides standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB43080
BF2d
Anticancer Cell-penetrating Peptides
Cancer-related peptides Delivery and barrier-penetrating peptides
CancerPPD 2.0 Peptipedia SATPdb dbACP CellPPD CellPPD-MOD CPPsite3.0 PerseuCPP
standard
No
A 24-aa standard natural multi-activity (Anticancer and Cell-penetrating Peptides) peptide sequence curated from CancerPPD 2.0, Peptipedia, SATPdb, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
TRSSRAGLQWPVGRVHRLLRKGGC-NH2
Physicochemical Analysis
C115H196N44O29S1
NDEIMFY
R
2691.16
12.58
7
0
7
+6
3.67
-0.642
77.08
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
5500
204.37
5
Residue Composition
number
1
A
5
R
0
N
0
D
1
C
0
E
1
Q
4
G
1
H
0
I
3
L
1
K
0
M
0
F
1
P
2
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 4 H: 1 I: 0 L: 3 K: 1 M: 0 F: 0 P: 1 S: 2 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
24
C115H196N44O29S1
2691.16
12.58
+6
3.67
-0.642
Amidation
L
Linear
Free
Antimicrobial
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

at 1 µM 90-100% viablity
Anticancer

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT/MTS assay
6-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2003

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

at 10 µM 90-95% viablity
Anticancer

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT/MTS assay
6-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2003
Evidence 3 Activity

Activity

at 100 µM 90-100% viablity
Anticancer

Target

Cervical Cancer
HeLa
Cervix

Assay & Model

MTT/MTS assay
6-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2003