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Peptide record

TPDB43071

Anticancer Tumor-homing Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB43071
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 20-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
TPLFCGNHGRQPSPLCMKWD
Physicochemical Analysis
C100H151N29O27S3
AEIYV
P
2287.66
8.30
3
1
5
+1
1.82
-0.640
39.00
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
5625
245.88
6
Residue Composition
number
0
A
1
R
1
N
1
D
2
C
0
E
1
Q
2
G
1
H
0
I
2
L
1
K
1
M
1
F
3
P
1
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 1 C: 2 E: 0 Q: 1 G: 2 H: 1 I: 0 L: 2 K: 1 M: 1 F: 1 P: 3 S: 1 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
20
C100H151N29O27S3
2287.66
8.30
+1
1.82
-0.640
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing (Phage display clone)
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of tumor-binding ligands in cancer patients with phage display libraries
2006
Krag DN et al. Cancer Res. 2006 Aug 1 66(15):7724-33.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
Phage display library
M13 phage/Random 20 mer (X4CX10CX4) peptide library
Additional Detail Fields 2 fields
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
M13 phage/Random 20 mer (X4CX10CX4) peptide library