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Peptide record

TPDB43069

Anticancer Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB43069
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 7-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
TLTYTWS
Physicochemical Analysis
C41H58N8O13
ARNDCEQGHIKMFPV
T
870.96
5.94
0
0
3
-0
-2.80
-0.186
55.71
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
6990
802.57
5
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
1
S
3
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 1 T: 3 W: 1 Y: 1 V: 0
Chemical Descriptors
7
C41H58N8O13
870.96
5.94
-0
-2.80
-0.186
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Tumor angiogenesis
MMP-2-processed collagen IV

Source & Reference

TumorHoPe2.0
TumorHoPe2
Targeting of tumor blood vessels: a phage-displayed tumor-homing peptide specifically binds to matrix metalloproteinase-2-processed collagen IV and blocks angiogenesis in vivo
2009
Mueller J et al. Mol Cancer Res. 2009 Jul 7(7):1078-85.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Murine LCC cells
Lewis lung carcinoma (LLC) tumor-bearing mice
Phage display library
M13 phage/ 7mer peptide library
Additional Detail Fields 3 fields
Murine LCC cells
Lewis lung carcinoma (LLC) tumor-bearing mice
M13 phage/ 7mer peptide library