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Peptide record

TPDB43056

ATMP1 ATMP5 Anticancer standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB43056
ATMP1 ATMP5
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 24-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
THPPTTTTTTTTTTTYTAAPATTT
Physicochemical Analysis
C103H166N26O42
RNDCEQGILKMFSWV
T
2440.60
7.77
1
0
4
+0
3.10
-0.629
12.50
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
1490
61.05
17
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
3
P
0
S
16
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 3 S: 0 T: 16 W: 0 Y: 1 V: 0
Chemical Descriptors
24
C103H166N26O42
2440.60
7.77
+0
3.10
-0.629
Free
L
Linear
Free
Anticancer Antimicrobial
Synthetic Analog of ATMP1 Anabas testudineus
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 64.04 ± 0.021 µg /ml
Anticancer
64.04

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 8.25 ± 0.14 µg/ml
Anticancer
8.25

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023