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Peptide record

TPDB43053

AtMP2 Anticancer standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB43053
AtMP2
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 22-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
TGIATSGLATFTLHTGSLAPAT
Physicochemical Analysis
C92H150N24O31
RNDCEQKMWYV
T
2088.35
7.85
1
0
9
+0
-1.26
0.641
89.09
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
8
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
1
H
1
I
3
L
0
K
0
M
1
F
1
P
2
S
6
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 1 I: 1 L: 3 K: 0 M: 0 F: 1 P: 1 S: 2 T: 6 W: 0 Y: 0 V: 0
Chemical Descriptors
22
C92H150N24O31
2088.35
7.85
+0
-1.26
0.641
Free
L
Linear
Free
Antimicrobial and Anticancer
Anabastestudineus skin mucus fraction 2
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
IC50 = 5.89 ± 0.14 µg/ml
Anticancer
5.89

Target

Breast Cancer
MCF-7
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 6.97 ± 0.24 µg/ml
Anticancer
6.97

Target

Breast Cancer
MDA-MB-231
Breast

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2021