Back to search

Peptide record

TPDB43049

hP3 Anticancer standard
25 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB43049
hP3
Anticancer
Cancer-related peptides
ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 Peptipedia SATPdb dbACP iACP-DRLF pep-lab
standard
No
A 25-aa standard natural anticancer peptide sequence curated from ACP740 _ACP240, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
TFRAFLSSRLQDLYSIVRRADRAAV
Physicochemical Analysis
C129H211N41O36
NCEGHKMPW
R
2912.35
11.81
5
2
13
+3
1.89
-0.012
101.60
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
1490
51.16
6
Residue Composition
number
4
A
5
R
0
N
2
D
0
C
0
E
1
Q
0
G
0
H
1
I
3
L
0
K
0
M
2
F
0
P
3
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 4 R: 5 N: 0 D: 2 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 3 K: 0 M: 0 F: 2 P: 0 S: 3 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
25
C129H211N41O36
2912.35
11.81
+3
1.89
-0.012
Free
L
Linear
Free
Antiangiogenesis
Human endostatin peptides
Evidence Records 1 records
Evidence 1 Activity

Activity

No inhibition at 7 mg/kg/d
Anticancer

Target

Pancreatic Cancer
BxPC-3
Pancreatic

Assay & Model

Matrigel Assay
672-h

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2005

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.