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Peptide record

TPDB43047

LJP-12 Anticancer standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB43047
LJP-12
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 5-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
TFKHG
Physicochemical Analysis
C27H40N8O7
ARNDCEQILMPSWYV
GHKFT
588.66
10.10
2
0
1
+1
0.97
-1.080
0.00
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
0
I
0
L
1
K
0
M
1
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 0 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C27H40N8O7
588.66
10.10
+1
0.97
-1.080
Free
L
Linear
Free
Anticancer
Laminaria japonica
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
IC50 = 0.41 ± 0.04 mM
Anticancer
0.41

Target

Liver Cancer
Huh-7
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

IC50
IC50 = 0.60 ± 0.08 mM
Anticancer
0.60

Target

Liver Cancer
HepG-2
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022
Evidence 3 Activity

Activity

IC50
IC50 = 0.72 ± 0.05 mM
Anticancer
0.72

Target

Liver Cancer
H-22
Liver

Assay & Model

MTT assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2022