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Peptide record

TPDB43038

PC5-2 Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB43038
PC5-2
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
TDSILRSYDWTY
Physicochemical Analysis
C69H98N16O23
ANCEQGHKMFPV
DSTY
1519.63
3.88
1
2
5
-1
-0.79
-0.808
65.00
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
8480
558.03
6
Residue Composition
number
0
A
1
R
0
N
2
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
0
K
0
M
0
F
0
P
2
S
2
T
1
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 2 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 0 S: 2 T: 2 W: 1 Y: 2 V: 0
Chemical Descriptors
12
C69H98N16O23
1519.63
3.88
-1
-0.79
-0.808
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Lung cancer, Breast cancer, Liver cancer, Melanoma, stomach cancer, Pancreatic cancer, Colorectal cancer, Ovarian cancer, Renal cell carcinoma, Prostate cancer, Brain tumor

Source & Reference

TumorHoPe2.0
TumorHoPe2
Noxa-derived, cell death-inducing peptide eMTD
2022
US 11248024 B2
US 11248024 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Sp2/0, CHO (Chinese hamster ovary) K1, CHO DG44, PER.C6, W138, BHK, COS7, 293, HepG2, Huh7, 3T3, RIN, MDCK cell line
6-week-old BalB/C mice
Synthetic
necrosis-inducing peptide, Fluorescein (FAM)
Additional Detail Fields 3 fields
necrosis-inducing peptide, Fluorescein (FAM)
Sp2/0, CHO (Chinese hamster ovary) K1, CHO DG44, PER.C6, W138, BHK, COS7, 293, HepG2, Huh7, 3T3, RIN, MDCK cell line
6-week-old BalB/C mice