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Peptide record

TPDB43027

PC4-9 Anticancer Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB43027
PC4-9
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 12-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
SYPLSFLGPLIS
Physicochemical Analysis
C63H96N12O17
ARNDCEQHKMTWV
LS
1293.53
5.94
0
0
6
-0
-2.76
0.950
130.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
1490
115.19
4
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
3
L
0
K
0
M
1
F
2
P
3
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 3 K: 0 M: 0 F: 1 P: 2 S: 3 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
12
C63H96N12O17
1293.53
5.94
-0
-2.76
0.950
WTYY
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Lung cancer, non-small cell lung cancer (NSCLC)

Source & Reference

TumorHoPe2.0
TumorHoPe2
A Novel Peptide Enhances Therapeutic Efficacy of Liposomal Anti-Cancer Drugs in Mice Models of Human Lung Cancer
2009
Chang DK et al. PLoS One. 2009 4(1):e4171.
US 2008/0193375A1

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
CL1-5, PC13, Specimens of pulmonary adenocarcinoma
Phage display library
M15 phage /random peptide library
Additional Detail Fields 2 fields
CL1-5, PC13, Specimens of pulmonary adenocarcinoma
M15 phage /random peptide library