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Peptide record

TPDB42993

Anticancer Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB42993
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 7-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
SRESPHP
Physicochemical Analysis
C33H52N12O12
ANDCQGILKMFTWYV
PS
808.85
7.85
2
1
0
+0
4.95
-2.286
0.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
1
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
2
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C33H52N12O12
808.85
7.85
+0
4.95
-2.286
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
Medullary thyroid carcinoma (MTC)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Discovery of targeting peptides for selective therapy of medullary thyroid carcinoma
2005
Bockmann M et al. J Gene Med. 2005 Feb 7(2):179-88.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human TT cells, 293 cells (Ad5 E1-transformed human embryonic kidney cells), H1299 (human bronchoalveolar carcinoma) VH6 cells (human primary foreskin fibroblasts)
Phage display library
M13 phage /C7C peptide library
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Homing
Medullary thyroid carcinoma

Source & Reference

TumorHoPe2.0
TumorHoPe2
Novel SRESPHP peptide mediates specific binding to primary medullary thyroid carcinoma after systemic injection
2005
Bockmann M et al. Hum Gene Ther. 2005 Nov 16(11):1267-75.

Other

Human Medullary thyroid Carcinoma cells
Orthotopically grown murine MTC RET-C634R transgenic mice
Phage display library
Additional Detail Fields 3 fields
Human TT cells, 293 cells (Ad5 E1-transformed human embryonic kidney cells), H1299 (human bronchoalveolar carcinoma) VH6 cells (human primary foreskin fibroblasts) Human Medullary thyroid Carcinoma cells
Orthotopically grown murine MTC RET-C634R transgenic mice
M13 phage /C7C peptide library