Back to search

Peptide record

TPDB42960

Clone G3-A3 Anticancer Tumor-homing Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB42960
Clone G3-A3
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 15-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
SMEPALPDWWWKMFK
Physicochemical Analysis
C95H130N20O21S2
RNCQGHITYV
W
1952.32
6.99
2
2
8
-0
-1.61
-0.620
32.67
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
16500
845.15
1
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
1
E
0
Q
0
G
0
H
0
I
1
L
2
K
2
M
1
F
2
P
1
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 2 M: 2 F: 1 P: 2 S: 1 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
15
C95H130N20O21S2
1952.32
6.99
-0
-1.61
-0.620
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell and tumor cell
Targeting
Tumor metastasis
Galectin-3

Source & Reference

TumorHoPe2.0
TumorHoPe2
Peptides specific to the galectin-3 carbohydrate recognition domain inhibit metastasis-associated cancer cell adhesion
2005
Zou J et al. Carcinogenesis. 2005 Feb 26(2):309-18.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 3
Phage display library
f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library
Additional Detail Fields 2 fields
Human breast cancer cell lines BT549, express detectable levels of galectin-3, BT549trans express galactein 3
f88 phage/15mer peptide library and f88 phage/Cys6 mer peptide library