TPDB

3D PDB MODEL

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TPDB ID TPDB42949

Activity

Anticancer

Activity_category_statistics

Cancer-related peptides

Database_Source

CancerPPD 2.0 dbACP

Sequence_Type

standard

Has_Modification No

Description A 43-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0 and dbACP, with an available 3D structural model.

Sequence

SKWQHQQDSCRKQLQGVNLTPCEKHIMEKIQGRDDDDDDDDDD

FASTA

>TPDB42949|Anticancer|length=43
SKWQHQQDSCRKQLQGVNLTPCEKHIMEKIQGRDDDDDDDDDD

Formula C206H323N65O80S3

Absent Amino Acids AFY

Common Amino Acids D

Mass 5086.40

PI 4.13

Basic Residues 8

Acidic Residues 13

Hydrophobic Residues 7

Net Charge -7

Boman Index 25.61

Hydrophobicity -1.835

Aliphatic Index 43.02

Half Life

Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 5625

Absorbance 280nm 110.59

Polar Residues 12

number

0

A

2

R

1

N

11

D

2

C

2

E

6

Q

2

G

2

H

2

I

2

L

4

K

1

M

0

F

1

P

2

S

1

T

1

W

0

Y

1

V

Amino Acid Distribution

A: 0 R: 2 N: 1 D: 11 C: 2 E: 2 Q: 6 G: 2 H: 2 I: 2 L: 2 K: 4 M: 1 F: 0 P: 1 S: 2 T: 1 W: 1 Y: 0 V: 1

Length

43

Formula

C206H323N65O80S3

Mass

5086.40

PI

4.13

Net Charge

-7

Boman Index

25.61

Hydrophobicity

-1.835

Evidence 1 Activity

Source & Reference

Database Source CancerPPD 2.0 dbACP

Other

Source Activity Label	Source Definition
Anticancer	CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.