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Peptide record

TPDB42943

Anticancer Tumor-homing Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB42943
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 20-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
Sequence
SIVNCSAALTDLPTRCGGNI
Physicochemical Analysis
C82H141N25O29S2
EQHKMFWY
ANCGILST
2005.29
5.95
1
1
7
-0
1.40
0.450
102.50
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
125
6.23
8
Residue Composition
number
2
A
1
R
2
N
1
D
2
C
0
E
0
Q
2
G
0
H
2
I
2
L
0
K
0
M
0
F
1
P
2
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 2 D: 1 C: 2 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 2 K: 0 M: 0 F: 0 P: 1 S: 2 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
20
C82H141N25O29S2
2005.29
5.95
-0
1.40
0.450
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing (Phage display clone)
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selection of tumor-binding ligands in cancer patients with phage display libraries
2006
Krag DN et al. Cancer Res. 2006 Aug 1 66(15):7724-33.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
Phage display library
M13 phage/Random 20 mer (X4CX10CX4) peptide library
Additional Detail Fields 2 fields
Patient biopsies, cancer cell line (breast: SK-BR-3), T47D, BT474, MDA-MB-231 and MDA-MB-361
M13 phage/Random 20 mer (X4CX10CX4) peptide library