Peptide record

TPDB42922

Anticancer Tumor-homing Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB42922
Anticancer Tumor-homing Peptides
Cancer-related peptides
Peptipedia StackTHP StackTHPred TumorHoPe2.0
standard
No
A 6-aa standard natural multi-activity (Anticancer and Tumor-homing Peptides) peptide sequence curated from Peptipedia, StackTHP, StackTHPred, and other sources, with an available 3D structural model.
N-terminal: H2N-e9-(ahx)-X6-r9-(Cy5-labeled d-cysteinamide)
Sequence
RWRTNF
Physicochemical Analysis
C40H58N14O9
ADCEQGHILKMPSYV
R
878.99
12.40
2
0
2
+2
-0.80
-1.883
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
625.72
2
Residue Composition
number
0
A
2
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
6
C40H58N14O9
878.99
12.40
+2
-0.80
-1.883
H2N-e9-(ahx)-X6-r9-(Cy5-labeled d-cysteinamide)
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Parallel in vivo and in vitro selection using phage display identifies protease-dependent tumor-targeting peptides
2010
Whitney M et al. J Biol Chem. 2010 Jul 16 285(29):22532-41.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
PyMT mice with mammary tumors
Phage display library
M13 phage/Met-His6-E9-X6-R9 peptide library
Cy5
Additional Detail Fields 3 fields
Cy5
PyMT mice with mammary tumors
M13 phage/Met-His6-E9-X6-R9 peptide library