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Peptide record

TPDB42893

2D5(G45-Y51) Anticancer standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB42893
2D5(G45-Y51)
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 17-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
Sequence
RRRRRRRRGGGLTIYFY
Physicochemical Analysis
C97H163N41O21
ANDCEQHKMPSWV
R
2239.62
12.62
8
0
5
+8
2.77
-1.729
45.88
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
2980
133.06
3
Residue Composition
number
0
A
8
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
1
I
1
L
0
K
0
M
1
F
0
P
0
S
1
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 1 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 2 V: 0
Chemical Descriptors
17
C97H163N41O21
2239.62
12.62
+8
2.77
-1.729
Free
L
Linear
Free
Anticancer
STAP-2 PH domain–derived peptide
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 19.4 µM
Anticancer
19.4 µM

Target

Liver Cancer
DU-145
Liver

Assay & Model

CellTiter-Glo assay
48-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.