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Peptide record

TPDB42883

Aurein 1.2_mutant_R5 (R5-Aurm) Anticancer standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB42883
Aurein 1.2_mutant_R5 (R5-Aurm)
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 18-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
N-terminal: Acetylation
Sequence
Ac-RRRRRGLFDIIKKIIKSF
Physicochemical Analysis
C105H184N36O22
ANCEQHMPTWYV
R
2302.84
12.59
8
1
7
+7
4.33
-0.639
108.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
5
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
4
I
1
L
3
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 4 L: 1 K: 3 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C105H184N36O22
2302.84
12.59
+7
4.33
-0.639
Free
L
Linear
Acetylation
Antimicrobial
Synthetic
Evidence Records 2 records
Evidence 1 Activity

Activity

40.62% cell viability
Anticancer

Target

Colon Cancer
SW-480
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

54.22% cell viability
Anticancer

Target

Colon Cancer
HT-29
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023