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Peptide record

TPDB42882

Aurein 1.2_R5 (R5-Aur) Anticancer standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB42882
Aurein 1.2_R5 (R5-Aur)
Anticancer
Cancer-related peptides
CancerPPD 2.0
standard
No
A 18-aa standard natural anticancer peptide sequence curated from CancerPPD 2.0, with an available 3D structural model.
N-terminal: Acetylation
Sequence
Ac-RRRRRGLFDIIKKIAESF
Physicochemical Analysis
C101H173N35O24
NCQHMPTWYV
R
2261.70
12.24
7
2
7
+5
5.50
-0.767
92.22
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
5
R
0
N
1
D
0
C
1
E
0
Q
1
G
0
H
3
I
1
L
2
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 1 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 3 L: 1 K: 2 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C101H173N35O24
2261.70
12.24
+5
5.50
-0.767
Free
L
Linear
Acetylation
Antimicrobial
Synthetic
Evidence Records 2 records
Evidence 1 Activity

Activity

43.89% cell viability
Anticancer

Target

Colon Cancer
SW-480
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

61.56% cell viability
Anticancer

Target

Colon Cancer
HT-29
Colon

Assay & Model

MTT assay
24-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2023